Background:

PROC encodes a vitamin K-dependent plasma glycoprotein. The vitamin K-dependent protein C is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.

Classification:

Primary antibody

Alternative names:

PROC; Vitamin K-dependent protein C; Anticoagulant protein C; Autoprothrombin IIA; Blood coagulation factor XIV

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from the Internal region of human PROC. AA range:181-230

Concentration:

1 mg/ml

Molecular weight:

52071

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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