Background:

BTC encodes a member of the epidermal growth factor (EGF) family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. A secreted form and a membrane-anchored form of this protein bind to multiple different EGF receptors. This protein promotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. Mutations in this gene may be associated with type 2 diabetes in human patients.

Classification:

Primary antibody

Alternative names:

BTC; Probetacellulin

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from the Internal region of human BTC. AA range:21-70

Concentration:

1 mg/ml

Molecular weight:

19746

Applications:

WB, ELISA

Storage:

-20°C for one year

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