Background:

BTC encodes a member of the epidermal growth factor (EGF) family of proteins. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate the secreted growth factor. A secreted form and a membrane-anchored form of betacellulin bind to multiple different EGF receptors. Betacellulin romotes pancreatic cell proliferation and insulin secretion, as well as retinal vascular permeability. Mutations in BTC may be associated with type 2 diabetes in human patients.

Classification:

Primary antibody

Alternative names:

BTC; Probetacellulin

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from Probetacellulin . at AA range: 60-140

Concentration:

1 mg/ml

Molecular weight:

19746

Applications:

WB, ELISA

Storage:

-20°C for one year

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