Background:

POT1 is a member of the telombin family and encodes a nuclear protein involved in telomere maintenance. Specifically, protection of telomeres 1 functions as a member of a multi-protein complex that binds to the TTAGGG repeats of telomeres, regulating telomere length and protecting chromosome ends from illegitimate recombination, catastrophic chromosome instability, and abnormal chromosome segregation. Increased transcriptional expression of POT1 is associated with stomach carcinogenesis and its progression.

Classification:

Primary antibody

Alternative names:

POT1; Protection of telomeres protein 1; hPot1; POT1-like telomere end-binding protein

Species reactivity:

Human;Monkey

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human POT1. AA range:247-296

Concentration:

1 mg/ml

Molecular weight:

71442

Applications:

WB, ELISA

Storage:

-20°C for one year

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