Background:

Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZCCHC17 (zinc finger, CCHC domain containing 17), also known as PS1D (putative S1 RNA-binding domain protein), Pnn (Pinin)-interacting nucleolar protein or pNO40, is a 241 amino acid protein that associates with both Pinin and the 60S ribosomal subunit. Localizing to nucleolus, ZCCHC17 is ubiquitously expressed and has been suggested to play a role in ribosome maturation and biogenesis. ZCCHC17 contains one CCHC-type zinc finger, a S1 motif domain and exists as two alternatively spliced isoforms that map to human chromosome 1p35.2. Human chromosome 1 spans 260 million base pairs, contains over 3000 genes, comprises nearly 8% of the human genome and houses a large number of disease-associated genes, including those that are involved in Stickler syndrome, Parkinson's disease, Gaucher disease and Usher syndrome.

Classification:

Primary antibody

Alternative names:

ZCCHC17; PS1D; HSPC243; HSPC251; LDC4; Nucleolar protein of 40 kDa; pNO40; Pnn-interacting nucleolar protein; Putative S1 RNA-binding domain protein; PS1D protein; Zinc finger CCHC domain-containing p

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human ZCCHC17. AA range:51-100

Concentration:

1 mg/ml

Molecular weight:

27570

Applications:

IHC-p, ELISA

Storage:

-20°C for one year

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