Background:

PKP2 encodes a member of the arm-repeat (armadillo) and plakophilin gene families. Plakophilin proteins contain numerous armadillo repeats, localize to cell desmosomes and nuclei, and participate in linking cadherins to intermediate filaments in the cytoskeleton. PKP2 product may regulate the signaling activity of beta-catenin. Two alternately spliced transcripts encoding two protein isoforms have been identified. A processed pseudogene with high similarity to this locus has been mapped to chromosome 12p13.

Classification:

Primary antibody

Alternative names:

PKP2; Plakophilin-2

Species reactivity:

Human;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human PKP2. AA range:632-681

Concentration:

1 mg/ml

Molecular weight:

97399

Applications:

WB, ELISA

Storage:

-20°C for one year

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