Background:

PKM encodes a protein involved in glycolysis. Pyruvate kinase, muscleprovided by is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP, generating ATP and pyruvate. Pyruvate kinase, muscleprovided by has been shown to interact with thyroid hormone and may mediate cellular metabolic effects induced by thyroid hormones. Pyruvate kinase, muscleprovided by has been found to bind Opa protein, a bacterial outer membrane protein involved in gonococcal adherence to and invasion of human cells, suggesting a role of pyruvate kinase, muscleprovided by in bacterial pathogenesis. Several alternatively spliced transcript variants encoding a few distinct isoforms have been reported

Classification:

Primary antibody

Alternative names:

PKM; OIP3; PK2; PK3; PKM2; Pyruvate kinase isozymes M1/M2; Cytosolic thyroid hormone-binding protein; CTHBP; Opa-interacting protein 3; OIP-3; Pyruvate kinase 2/3; Pyruvate kinase muscle isozyme; Thyr

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human PKM2. AA range:181-230

Concentration:

1 mg/ml

Molecular weight:

57937

Applications:

IF, WB, IHC-p, ELISA

Storage:

-20°C for one year

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