Background:

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. Protein kinase C delta by PRKCD is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed.

Classification:

Primary antibody

Alternative names:

PRKCD; Protein kinase C delta type; Tyrosine-protein kinase PRKCD; nPKC-delta

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human PKC delta. AA range:612-661

Concentration:

1 mg/ml

Molecular weight:

77477

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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