Background:

PIAS3 encodes a member of the PIAS [protein inhibitor of activated STAT (signal transducer and activator of transcription)] family of transcriptional modulators. Protein inhibitor of activated STAT 3 functions as a SUMO (small ubiquitin-like modifier)-E3 ligase which catalyzes the covalent attachment of a SUMO protein to specific target substrates. It directly binds to several transcription factors and either blocks or enhances their activity. Alternatively spliced transcript variants of PIAS3 have been identified, but the full-length nature of some of these variants has not been determined.

Classification:

Primary antibody

Alternative names:

PIAS3; E3 SUMO-protein ligase PIAS3; Protein inhibitor of activated STAT protein 3

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human PIAS3. AA range:10-59

Concentration:

1 mg/ml

Molecular weight:

68017

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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