Background:

Phosphoinositide 3-kinases (PI3Ks) phosphorylate inositol lipids and are involved in the immune response. The protein encoded by PIK3CG (phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma) is a class I catalytic subunit of PI3K. Like other class I catalytic subunits (p110-alpha p110-beta, and p110-delta), the encoded protein binds a p85 regulatory subunit to form PI3K. This gene is located in a commonly deleted segment of chromosome 7 previously identified in myeloid leukemias. Several transcript variants encoding the same protein have been found for PIK3CG.

Classification:

Primary antibody

Alternative names:

PIK3R2; Phosphatidylinositol 3-kinase regulatory subunit beta; PI3-kinase regulatory subunit beta; PI3K regulatory subunit beta; PtdIns-3-kinase regulatory subunit beta; Phosphatidylinositol 3-kinase

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

Recombinant Protein of PI 3-Kinase p85β

Concentration:

1 mg/ml

Molecular weight:

81624

Applications:

WB, IHC-p

Storage:

-20°C for one year

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