Background:

Prostaglandin E synthase encoded by PTGES is a glutathione-dependent prostaglandin E synthase. The expression of PTGES has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that PTGES may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses.

Classification:

Primary antibody

Alternative names:

PTGES; MGST1L1; MPGES1; PGES; PIG12; Prostaglandin E synthase; Microsomal glutathione S-transferase 1-like 1; MGST1-L1; Microsomal prostaglandin E synthase 1; MPGES-1; p53-induced gene 12 protein

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human PGE synthase. AA range:30-79

Concentration:

1 mg/ml

Molecular weight:

17102

Applications:

WB, ELISA

Storage:

-20°C for one year

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