Background:

6-phosphogluconate dehydrogenase (PGD) is the second dehydrogenase in the pentose phosphate shunt. Deficiency of this enzyme is generally asymptomatic, and the inheritance of this disorder is autosomal dominant. Hemolysis results from combined deficiency of 6-phosphogluconate dehydrogenase and 6-phosphogluconolactonase suggesting a synergism of the two enzymopathies. Several transcript variants encoding different isoforms have been found for this gene.

Classification:

Primary antibody

Alternative names:

PGD; PGDH; 6-phosphogluconate dehydrogenase; decarboxylating

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human PGD. AA range:71-120

Concentration:

1 mg/ml

Molecular weight:

53140

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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