Background:

PER2 (period circadian clock 2) is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. PER2 is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in PER2 may increase the risk of getting certain cancers and have been linked to sleep disorders.

Classification:

Primary antibody

Alternative names:

PER2; KIAA0347; Period circadian protein homolog 2; hPER2; Circadian clock protein PERIOD 2

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human Period Circadian Protein 2. AA range:636-685

Concentration:

1 mg/ml

Molecular weight:

136579

Applications:

IHC-p, IF, ELISA

Storage:

-20°C for one year

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