Background:

PDK2 encodes a member of the pyruvate dehydrogenase kinase family. Pyruvate dehydrogenase kinase 2 phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of PDK2 may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for PDK2.

Classification:

Primary antibody

Alternative names:

PDK2; PDHK2; [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 2; mitochondrial; Pyruvate dehydrogenase kinase isoform 2

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human PDK2. AA range:260-309

Concentration:

1 mg/ml

Molecular weight:

46154

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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