Background:

Present mainly in the mitochondrial compartment of peripheral tissues, the protein encoded by TSPO (translocator protein) interacts with some benzodiazepines and has different affinities than its endogenous counterpart. The protein is a key factor in the flow of cholesterol into mitochondria to permit the initiation of steroid hormone synthesis. Alternatively spliced transcript variants have been reported; one of the variants lacks an internal exon and is considered non-coding, and the other variants encode the same protein.

Classification:

Primary antibody

Alternative names:

TSPO; BZRP; MBR; Translocator protein; Mitochondrial benzodiazepine receptor; PKBS; Peripheral-type benzodiazepine receptor; PBR

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from PBR . at AA range: 90-170

Concentration:

1 mg/ml

Molecular weight:

18779

Applications:

WB, ELISA

Storage:

-20°C for one year

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