Background:

PBK (PDZ binding kinase) encodes a serine/threonine protein kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. The encoded protein may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. Overexpression of PBK has been implicated in tumorigenesis. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

PBK; TOPK; Lymphokine-activated killer T-cell-originated protein kinase; Cancer/testis antigen 84; CT84; MAPKK-like protein kinase; Nori-3; PDZ-binding kinase; Spermatogenesis-related protein kinase;

Species reactivity:

Human;Monkey

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human PBK/TOPK. AA range:1-50

Concentration:

1 mg/ml

Molecular weight:

36085

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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