Background:

PAX8 encodes a member of the paired box (PAX) family of transcription factors. Members of PAX8 family typically encode proteins that contain a paired box domain, an octapeptide, and a paired-type homeodomain. This nuclear protein is involved in thyroid follicular cell development and expression of thyroid-specific genes. Mutations in PAX8 have been associated with thyroid dysgenesis, thyroid follicular carcinomas and atypical follicular thyroid adenomas. Alternatively spliced transcript variants encoding different isoforms have been described.

Classification:

Primary antibody

Alternative names:

PAX8; Paired box protein Pax-8

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human Pax-8. AA range:145-194

Concentration:

1 mg/ml

Molecular weight:

48119

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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