Background:

Inner membrane mitochondrial proteins are responsible for the transport of metabolites across the mitochondrial membrane. SLC25A11 (Solute carrier family 25 member 11), also known as Mitochondrial 2-oxoglutarate/malate carrier protein, is a 314 amino acid multi-pass transmembrane protein belonging to the mitochondrial carrier protein family. As an oxoglutarate/malate carrier, SLC25A11 transports 2-oxoglutarate across the inner mitochondrial membrane in an electroneutral exchange for dicarboxylic acids and malate. SLC25A11 also participates in other important metabolic processes, such as the oxoglutarate/isocitrate shuttle and the malate-aspartate shuttle, as well as in nitrogen metabolism and in gluconeogenesis from lactate. SLC25A11 contains 3 solcar repeats, which is typical of substrate carrier proteins involved in energy transfer.

Classification:

Primary antibody

Alternative names:

SLC25A11; SLC20A4; Mitochondrial 2-oxoglutarate/malate carrier protein; OGCP; Solute carrier family 25 member 11

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human SLC25A11. AA range:132-181

Concentration:

1 mg/ml

Molecular weight:

34062

Applications:

WB, ELISA

Storage:

-20°C for one year

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