Background:

OCRL encodes an inositol polyphosphate 5-phosphatase. OCRL, inositol polyphosphate-5-phosphatase is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. OCRL, inositol polyphosphate-5-phosphatase may also play a role in primary cilium formation. Mutations in OCRL cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

OCRL; INPP5F; OCRL1; Inositol polyphosphate 5-phosphatase OCRL-1; Lowe oculocerebrorenal syndrome protein

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human OCRL. AA range:150-199

Concentration:

1 mg/ml

Molecular weight:

104205

Applications:

WB, ELISA

Storage:

-20°C for one year

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