Background:

OPCML encodes a member of the IgLON subfamily in the immunoglobulin protein superfamily of proteins. Opioid binding protein/cell adhesion molecule like is proteolytically processed to generate the mature protein. Opioid binding protein/cell adhesion molecule like is localized in the plasma membrane and may have an accessory role in opioid receptor function. OPCML has an ortholog in rat and bovine. The opioid binding-cell adhesion molecule encoded by the rat gene binds opioid alkaloids in the presence of acidic lipids, exhibits selectivity for mu ligands and acts as a GPI-anchored protein. Since the opioid binding protein/cell adhesion molecule like is highly conserved in species during evolution, it may have a fundamental role in mammalian systems. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Classification:

Primary antibody

Alternative names:

OPCML; IGLON1; OBCAM; Opioid-binding protein/cell adhesion molecule; OBCAM; OPCML; Opioid-binding cell adhesion molecule; IgLON family member 1

Species reactivity:

Human;Mouse;Rat;Monkey

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human OBCAM. AA range:152-201

Concentration:

1 mg/ml

Molecular weight:

38008

Applications:

WB, ELISA

Storage:

-20°C for one year

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