Background:

The nuclear pore complex is a massive structure that extends across the nuclear envelope, forming a gateway that regulates the flow of macromolecules between the nucleus and the cytoplasm. Nucleoporins, a family of 50 to 100 proteins, are the main components of the nuclear pore complex in eukaryotic cells. Nuclear pore complex protein Nup88 encoded by NUP88 belongs to the nucleoporin family and is associated with the oncogenic nucleoporin CAN/Nup214 in a dynamic subcomplex. This protein is also overexpressed in a large number of malignant neoplasms and precancerous dysplasias. Alternative splicing results in multiple transcript variants encoding different isoforms.

Classification:

Primary antibody

Alternative names:

NUP88; Nuclear pore complex protein Nup88; 88 kDa nucleoporin; Nucleoporin Nup88

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from Nup88 . at AA range: 330-410

Concentration:

1 mg/ml

Molecular weight:

83542

Applications:

WB, ELISA

Storage:

-20°C for one year

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