Background:

NUMA1 encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of NUMA1 with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

NUMA1; NUMA; Nuclear mitotic apparatus protein 1; NuMA protein; SP-H antigen

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human NUMA1. AA range:334-383

Concentration:

1 mg/ml

Molecular weight:

238260

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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