Background:

NRTN encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. The encoded preproprotein is proteolytically processed to generate the mature protein. Neurturin signals through the RET receptor tyrosine kinase and a GPI-linked coreceptor, and promotes survival of neuronal populations. A neurturin mutation has been described in a family with Hirschsprung Disease.

Classification:

Primary antibody

Alternative names:

NRTN; Neurturin

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from the Internal region of human NRTN. AA range:111-160

Concentration:

1 mg/ml

Molecular weight:

22405

Applications:

WB, ELISA

Storage:

-20°C for one year

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