Background:

NFE2L2 encodes a transcription factor (nuclear factor, erythroid 2 like 2) which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been characterized for NFE2L2.

Classification:

Primary antibody

Alternative names:

NFE2L2; NRF2; Nuclear factor erythroid 2-related factor 2; NF-E2-related factor 2; NFE2-related factor 2; HEBP1; Nuclear factor, erythroid derived 2, like 2

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized acetyl-peptide derived from the C-terminal region of human Nrf2 around the acetylation site of K599.

Concentration:

1 mg/ml

Molecular weight:

75-100

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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