Background:

NMBR encodes a 7-transmembrane G protein-coupled receptor that binds neuromedin B, which is a growth factor and mitogen for gastrointestinal epithelial tissue and for normal and neoplastic lung. This receptor may play a role in smooth muscle contraction, neuronal responses, and the regulation of cell growth. Antagonists of this receptor have a potential therapeutic use in inhibiting tumor cell growth. Polymorphisms in NMBR may be associated with a susceptibility for schizophrenia. Alternative splicing of this gene results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

NMBR; Neuromedin-B receptor; NMB-R; Epididymis tissue protein Li 185a; Neuromedin-B-preferring bombesin receptor

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human NMBR. AA range:221-270

Concentration:

1 mg/ml

Molecular weight:

43453

Applications:

WB, IF, ELISA

Storage:

-20°C for one year

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