Background:

NFATC4 encodes a member of the nuclear factor of activated T cells (NFAT) protein family. Nuclear factor of activated T-cells cytoplasmic 4 is part of a DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor stimulation and an inducible nuclear component. NFAT proteins are activated by the calmodulin-dependent phosphatase, calcineurin. The encoded protein plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of interleukin-2 and interleukin-4. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

NFATC4; NFAT3; Nuclear factor of activated T-cells; cytoplasmic 4; NF-ATc4; NFATc4; T-cell transcription factor NFAT3; NF-AT3

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human NFAT3. AA range:642-691

Concentration:

1 mg/ml

Molecular weight:

95473

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for one year

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