Background:

NF1 product appears to function as a negative regulator of the ras signal transduction pathway. Mutations in this gene have been linked to neurofibromatosis type 1, juvenile myelomonocytic leukemia and Watson syndrome. The mRNA for this gene is subject to RNA editing (CGA>UGA->Arg1306Term) resulting in premature translation termination. Alternatively spliced transcript variants encoding different isoforms have also been described for this gene.

Classification:

Primary antibody

Alternative names:

NF1; Neurofibromin; Neurofibromatosis-related protein NF-1

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human NF1. AA range:1551-1600

Concentration:

1 mg/ml

Molecular weight:

319372

Applications:

WB, IF, ELISA

Storage:

-20°C for one year

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