Background:

NCALD (neurocalcin delta) encodes a member of the neuronal calcium sensor (NCS) family of calcium-binding proteins. The protein contains an N-terminal myristoylation signal and four EF-hand calcium binding loops. The protein is cytosolic at resting calcium levels; however, elevated intracellular calcium levels induce a conformational change that exposes the myristoyl group, resulting in protein association with membranes and partial co-localization with the perinuclear trans-golgi network. The protein is thought to be a regulator of G protein-coupled receptor signal transduction. Several alternatively spliced variants of NCALD have been determined, all of which encode the same protein; additional variants may exist but their biological validity has not been determined.

Classification:

Primary antibody

Alternative names:

NCALD; Neurocalcin-delta

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from Neurocalcin δ . at AA range: 370-450

Concentration:

1 mg/ml

Molecular weight:

22245

Applications:

IHC-p, ELISA

Storage:

-20°C for one year

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