Background:

NECTIN2 encodes a single-pass type I membrane glycoprotein with two Ig-like C2-type domains and an Ig-like V-type domain. Nectin cell adhesion molecule 2 is one of the plasma membrane components of adherens junctions. It also serves as an entry for certain mutant strains of herpes simplex virus and pseudorabies virus, and it is involved in cell to cell spreading of these viruses. Variations in this gene have been associated with differences in the severity of multiple sclerosis. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Classification:

Primary antibody

Alternative names:

PVRL2; HVEB; PRR2; Poliovirus receptor-related protein 2; Herpes virus entry mediator B; Herpesvirus entry mediator B; HveB; Nectin-2; CD112

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from Poliovirus receptor-related protein 2 at AA range: 151-200

Concentration:

1 mg/ml

Molecular weight:

57742

Applications:

WB, ELISA

Storage:

-20°C for one year

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