Background:

The protein encoded by NCOA3 (nuclear receptor coactivator 3) is a nuclear receptor coactivator that interacts with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has histone acetyltransferase activity and recruits p300/CBP-associated factor and CREB binding protein as part of a multisubunit coactivation complex. This protein is initially found in the cytoplasm but is translocated into the nucleus upon phosphorylation. Several transcript variants encoding different isoforms have been found for NCOA3. In addition, a polymorphic repeat region is found in the C-terminus of the encoded protein.

Classification:

Primary antibody

Alternative names:

NCOA3; AIB1; BHLHE42; RAC3; TRAM1; Nuclear receptor coactivator 3; NCoA-3; ACTR; Amplified in breast cancer 1 protein; AIB-1; CBP-interacting protein; pCIP; Class E basic helix-loop-helix protein 42;

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human NCoA-3. AA range:538-587

Concentration:

1 mg/ml

Molecular weight:

155293

Applications:

IHC-p, ELISA

Storage:

-20°C for one year

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