Background:

MYO9B encodes a member of the myosin family of actin-based molecular motor heavy chain proteins. The protein represents an unconventional myosin; it should not be confused with the conventional non-muscle myosin-9 (MYH9). The protein has four IQ motifs located in the neck domain that bind calmodulin, which serves as a light chain. The protein complex has a single-headed structure and exhibits processive movement on actin filaments toward the minus-end. The protein also has rho-GTPase activity. Polymorphisms in this gene are associated with celiac disease and ulcerative colitis susceptibility. Multiple transcript variants encoding different isoforms have been found for MYO9B.

Classification:

Primary antibody

Alternative names:

MYO9B; MYR5; Unconventional myosin-IXb; Unconventional myosin-9b

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human MYO9B. AA range:304-353

Concentration:

1 mg/ml

Molecular weight:

243558

Applications:

WB, ELISA

Storage:

-20°C for one year

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