Background:

Myogenic factor 6 encoded by MYF6 is a probable basic helix-loop-helix (bHLH) DNA binding protein involved in muscle differentiation. The encoded protein likely acts as a heterodimer with another bHLH protein. Defects in this gene are a cause of autosomal dominant centronuclear myopathy (ADCNM). Diseases associated with MYF6 include myopathy, centronuclear, 3 and myopathy, centronuclear. Among its related pathways are Developmental Biology and CDO in myogenesis. Gene Ontology (GO) annotations related to this gene include transcription factor activity, sequence-specific DNA binding and RNA polymerase II core promoter proximal region sequence-specific DNA binding. An important paralog of this gene is MYOD1.

Classification:

Primary antibody

Alternative names:

MYF6; BHLHC4; MRF4; Myogenic factor 6; Myf-6; Class C basic helix-loop-helix protein 4; bHLHc4; Muscle-specific regulatory factor 4

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human MYF6. AA range:116-165

Concentration:

1 mg/ml

Molecular weight:

26953

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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