Background:

MyD88 encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. Myeloid differentiation primary response protein MyD88 functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

MYD88; Myeloid differentiation primary response protein MyD88

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human MyD88. AA range:171-220

Concentration:

1 mg/ml

Molecular weight:

33233

Applications:

IF, WB, IHC-p, ELISA

Storage:

-20°C for one year

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