Background:

MSH2 is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E.coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.

Classification:

Primary antibody

Alternative names:

MSH2; DNA mismatch repair protein Msh2; hMSH2; MutS protein homolog 2

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human MSH2. AA range:541-590

Concentration:

1 mg/ml

Molecular weight:

104743

Applications:

IHC-p, IF, ELISA

Storage:

-20°C for one year

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