Background:

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPS5 (mitochondrial ribosomal protein S5) encodes a 28S subunit protein that belongs to the ribosomal protein S5P family. Pseudogenes corresponding to MRPS5 are found on chromosomes 4q, 5q, and 18q.

Classification:

Primary antibody

Alternative names:

MRPS5; 28S ribosomal protein S5; mitochondrial; MRP-S5; S5mt

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human MRPS5. AA range:367-416

Concentration:

1 mg/ml

Molecular weight:

48006

Applications:

IHC-p, ELISA

Storage:

-20°C for one year

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