Background:

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPS17 (mitochondrial ribosomal protein S17) encodes a 28S subunit protein that belongs to the ribosomal protein S17P family. The encoded protein is moderately conserved between human mitochondrial and prokaryotic ribosomal proteins. Pseudogenes corresponding to MRPS17 are found on chromosomes 1p, 3p, 6q, 14p, 18q, and Xq.

Classification:

Primary antibody

Alternative names:

MRPS17; RPMS17; HSPC011; 28S ribosomal protein S17; mitochondrial; MRP-S17; S17mt

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human MRPS17. AA range:11-60

Concentration:

1 mg/ml

Molecular weight:

14502

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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