Background:

Mammalian mitochondrial ribosomal protein L 50 (39S ribosomal protein L50 mitochondrial) is encoded by nuclear gene MRPL50 and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a putative 39S subunit protein and belongs to the L47P ribosomal protein family. Pseudogenes corresponding to this gene are found on chromosomes 2p, 2q, 5p, and 10q.

Classification:

Primary antibody

Alternative names:

MRPL50; 39S ribosomal protein L50; mitochondrial; L50mt; MRP-L50

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human MRPL50. AA range:109-158

Concentration:

1 mg/ml

Molecular weight:

18325

Applications:

WB, ELISA

Storage:

-20°C for one year

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