Background:

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. Pseudogenes corresponding to MRPL49 (mitochondrial ribosomal protein L49)are found on chromosomes 5q and 8p.

Classification:

Primary antibody

Alternative names:

MRPL49; C11orf4; NOF1; OK/SW-cl.67; 39S ribosomal protein L49; mitochondrial; L49mt; MRP-L49; Neighbor of FAU; NOF; Protein NOF1

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from MRP-L49 . at AA range: 10-90

Concentration:

1 mg/ml

Molecular weight:

19198

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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