Background:

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL48 (mitochondrial ribosomal protein L48) encodes a 39S subunit protein. A pseudogene corresponding to this gene is found on chromosome 6p. Several transcript variants, some protein-coding and some non-protein coding, have been found for this gene.

Classification:

Primary antibody

Alternative names:

MRPL48; CGI-118; HSPC290; 39S ribosomal protein L48; mitochondrial; L48mt; MRP-L48

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human MRPL48. AA range:161-210

Concentration:

1 mg/ml

Molecular weight:

23935

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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