Background:

Mammalian mitochondrial ribosomal protein L 46 (39S ribosomal protein L46 mitochondrial) is encoded by nuclear gene MRPL46 and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein.

Classification:

Primary antibody

Alternative names:

MRPL46; C15orf4; LIECG2; 39S ribosomal protein L46; mitochondrial; L46mt; MRP-L46; P2ECSL

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human MRPL46. AA range:111-160

Concentration:

1 mg/ml

Molecular weight:

31705

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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