Background:

Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. MRPL39 (mitochondrial ribosomal protein L39) encodes a 39S subunit protein. Two transcript variants encoding distinct isoforms have been described. A pseudogene corresponding to MRPL39 is found on chromosome 5q.

Classification:

Primary antibody

Alternative names:

MRPL39; C21orf92; MRPL5; RPML5; MSTP003; PRED22; 39S ribosomal protein L39; mitochondrial; L39mt; MRP-L39; 39S ribosomal protein L5, mitochondrial; L5mt; MRP-L5

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human MRPL39. AA range:289-338

Concentration:

1 mg/ml

Molecular weight:

38722

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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