Background:

Mammalian mitochondrial ribosomal protein L 21 (39S ribosomal protein L21 mitochondrial) is encoded by nuclear gene MRPL21 and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 39S subunit protein. Multiple transcript variants encoding different isoforms were identified through sequence analysis although some may be subject to nonsense-mediated decay (NMD).

Classification:

Primary antibody

Alternative names:

MRPL21; 39S ribosomal protein L21; mitochondrial; L21mt; MRP-L21

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human MRPL21. AA range:131-180

Concentration:

1 mg/ml

Molecular weight:

23159

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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