Background:

MPRIP (Myosin Phosphatase Rho Interacting Protein) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include actin binding. Targets myosin phosphatase to the actin cytoskeleton. Required for the regulation of the actin cytoskeleton by RhoA and ROCK1. Depletion leads to an increased number of stress fibers in smooth muscle cells through stabilization of actin fibers by phosphorylated myosin. Overexpression of MRIP as well as its F-actin-binding region leads to disassembly of stress fibers in neuronal cells.

Classification:

Primary antibody

Alternative names:

MPRIP; KIAA0864; MRIP; RHOIP3; Myosin phosphatase Rho-interacting protein; M-RIP; Rho-interacting protein 3; RIP3; p116Rip

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human MPRIP. AA range:723-772

Concentration:

1 mg/ml

Molecular weight:

116446

Applications:

IHC-p, WB, ELISA

Storage:

-20°C for one year

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