Background:

MFN2 encodes a mitochondrial membrane protein that participates in mitochondrial fusion and contributes to the maintenance and operation of the mitochondrial network. Mitofusin-2 is involved in the regulation of vascular smooth muscle cell proliferation, and it may play a role in the pathophysiology of obesity. Mutations in this gene cause Charcot-Marie-Tooth disease type 2A2, and hereditary motor and sensory neuropathy VI, which are both disorders of the peripheral nervous system. Defects in this gene have also been associated with early-onset stroke. Two transcript variants encoding the same protein have been identified.

Classification:

Primary antibody

Alternative names:

MFN2; CPRP1; KIAA0214; Mitofusin-2; Transmembrane GTPase MFN2

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human Mfn2. AA range:354-403

Concentration:

1 mg/ml

Molecular weight:

86402

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

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