Background:

ME2 encodes a mitochondrial NAD-dependent malic enzyme, a homotetrameric protein, that catalyzes the oxidative decarboxylation of malate to pyruvate. It had previously been weakly linked to a syndrome known as Friedreich ataxia that has since been shown to be the result of mutation in a completely different gene. Certain single-nucleotide polymorphism haplotypes of this gene have been shown to increase the risk for idiopathic generalized epilepsy. Alternatively spliced transcript variants encoding different isoforms found for this gene.

Classification:

Primary antibody

Alternative names:

ME2; NAD-dependent malic enzyme; mitochondrial; NAD-ME; Malic enzyme 2

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human ME2. AA range:201-250

Concentration:

1 mg/ml

Molecular weight:

65444

Applications:

WB, IHC-p, ELISA

Storage:

-20°C for one year

More info:

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