Background:

MARCH1 (membrane associated ring-CH-type finger 1) is a member of the MARCH family of membrane-bound E3 ubiquitin ligases. MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the late endosomal/lysosomal compartment.

Classification:

Primary antibody

Alternative names:

MARCH1; RNF171; E3 ubiquitin-protein ligase MARCH1; Membrane-associated RING finger protein 1; Membrane-associated RING-CH protein I; MARCH-I; RING finger protein 171

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from the Internal region of human 40603.

Concentration:

1 mg/ml

Molecular weight:

32308

Applications:

IHC-p, WB, ELISA

Storage:

-20°C for one year

More info:

Email: info@sobekbio.com

Orders:

Email: orders@sobekbio.com