Background:

The MAF bZIP transcription factor F encoded by MAFF is a basic leucine zipper (bZIP) transcription factor that lacks a transactivation domain. It is known to bind the US-2 DNA element in the promoter of the oxytocin receptor (OTR) gene and most likely heterodimerizes with other leucine zipper-containing proteins to enhance expression of the OTR gene during term pregnancy. The encoded protein can also form homodimers, and since it lacks a transactivation domain, the homodimer may act as a repressor of transcription. This gene may also be involved in the cellular stress response. Multiple transcript variants encoding two different isoforms have been found for this gene.

Classification:

Primary antibody

Alternative names:

MAFF; Transcription factor MafF; U-Maf; V-maf musculoaponeurotic fibrosarcoma oncogene homolog F

Species reactivity:

Human;Mouse

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human MAFF. AA range:51-100

Concentration:

1 mg/ml

Molecular weight:

17760

Applications:

IHC-p, ELISA

Storage:

-20°C for one year

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