Background:

GPM6A (Glycoprotein M6A) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include calcium channel activity. An important paralog of this gene is PLP1. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.

Classification:

Primary antibody

Alternative names:

GPM6A; M6A; Neuronal membrane glycoprotein M6-a; M6a

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

Synthesized peptide derived from M6A . at AA range: 140-220

Concentration:

1 mg/ml

Molecular weight:

31210

Applications:

WB, ELISA

Storage:

-20°C for one year

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