Background:

Lecithin retinol acyltransferase encoded by LRAT localizes to the endoplasmic reticulum, where it catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester. This reaction is an important step in vitamin A metabolism in the visual system. Mutations in this gene have been associated with early-onset severe retinal dystrophy and Leber congenital amaurosis 14. Alternative splicing results in multiple transcript variants.

Classification:

Primary antibody

Alternative names:

LRAT; Lecithin retinol acyltransferase; Phosphatidylcholine--retinol O-acyltransferase

Species reactivity:

Human;Mouse;Rat

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human LRAT. AA range:111-160

Concentration:

1 mg/ml

Molecular weight:

25703

Applications:

WB, IHC-p, IF, ELISA

Storage:

-20°C for one year

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