Background:

STK10 encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. Serine/threonine-protein kinase 10 can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. Serine/threonine-protein kinase 10 can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway.

Classification:

Primary antibody

Alternative names:

STK10; LOK; Serine/threonine-protein kinase 10; Lymphocyte-oriented kinase

Species reactivity:

Human

Host:

Rabbit

Isotype:

IgG

Immunogen:

The antiserum was produced against synthesized peptide derived from human STK10. AA range:491-540

Concentration:

1 mg/ml

Molecular weight:

112135

Applications:

WB, ELISA

Storage:

-20°C for one year

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